What is Nic Salt? Nicotine Salt E-Liquid also known as Nic Salts is salt-based nicotine without the coarse throat hit. Nic Salt E-Liquid vapes easier but you get more nicotine. Looking to switch to vaping? Nic Salts are typically an easier inhale with more nicotine per vape hit, nic salts as they are nicknamed are a great ejuice for folks looking for a satisfying high nicotine level that they used to get.